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China
Intelligence for Better Decision Making
China's First Domestic Mpox Vaccine Trials
Sept. 11, 2024 | Indirect Indicator- On September 9, the Shanghai Institute of Biological Products, part of Sinopharm Group China National Biotec Group, received clinical trial approval for its MVA strain monkeypox live attenuated vaccine from the National Medical Products Administration.
- This vaccine, the first monkeypox vaccine approved for clinical trials in China, aims to aid in disease prevention and control.
- The vaccine, based on a replication-deficient vaccinia virus MVA strain, has demonstrated safety and effectiveness in preclinical studies, providing good immune protection in non-human primate models.
- Since the global monkeypox outbreak in 2022, with over 100,000 confirmed cases worldwide, including 2,567 cases in China, the urgency for effective vaccines has increased.
- Despite several countries having approved monkeypox vaccines, China has not yet marketed any.
- The Shanghai Institute plans to expedite the clinical research and development of the vaccine to meet public health needs.
- This development marks a significant milestone in China's public health response to the virus, as China has initiated clinical trials for its first domestically developed monkeypox vaccine.
- The vaccine has been independently developed by the Shanghai Institute of Biological Products, a subsidiary of Sinopharm.
- The vaccine utilizes a live, attenuated strain of orthopoxvirus known as Modified Vaccinia Ankara (MVA), similar to the Jynneos vaccine approved in the U.S. in 2019.
- The World Health Organization (WHO) reported that from January 2022 to August 2024, more than 120 countries have had cases of monkeypox, with over 100,000 confirmed cases and more than 220 deaths.
- On August 14, the WHO elevated the status of monkeypox in the Democratic Republic of the Congo (DRC) and surrounding regions to a Public Health Emergency of International Concern.
- Lu Hongzhou, head of the Third People's Hospital of Shenzhen, emphasized vigilance due to the current focus on the outbreak in the DRC but assessed that the probability of a sudden increase in monkeypox infections in China remains relatively low.
- Monkeypox is transmitted through close contact and can enter the body through damaged skin and mucous membranes.
- Early symptoms of monkeypox resemble influenza, including fever, chills, headache, muscle aches, and fatigue.
- The Shanghai Institute's vaccine is anticipated to play a significant role in the prevention and control of monkeypox infections.
- Mpox, first identified in 1958, has led to multiple global outbreaks, with the most significant outbreak in China occurring between June and November of the previous year, resulting in 1,610 confirmed cases.
- From early 2023 to August 26, the Africa Centres for Disease Control and Prevention reported 22,863 mpox cases across Africa, with 622 associated deaths.
- In addition to traditional attenuated vaccines, pharmaceutical companies from both China and the United States are developing mpox vaccines using mRNA technology. Moderna is in early clinical trials for its mRNA mpox vaccine, while CNBG is advancing three candidates of mRNA mpox vaccines in mouse experiments.
Joint Naval and Air Drills between China and Russia
Sept. 11, 2024 | Government Actions- Russian military to send naval and air forces to participate in Northern/Interaction-2024 military drills in the Sea of Japan and Sea of Okhotsk in September, organized by China. These drills aim to enhance strategic cooperation between China and Russia and respond to security threats, forming part of an annual schedule based on mutual agreement.
- Russian and Chinese naval fleets will conduct their fifth joint maritime patrol in the Pacific Ocean, while the Chinese navy will also participate in Russia's "Ocean-2024" strategic exercise.
- Chinese state-run Xinhua news agency reported the upcoming joint military exercises in the Sea of Japan and Sea of Okhotsk.
- Russian drones recently infiltrated NATO airspace during an attack on Ukraine, prompting Romania to scramble F-16 jets. Additionally, Romania reported finding fragments from a Russian drone in a village near the Danube River and continues searching for additional debris. Latvia also reported a crashed drone in its eastern region following Russian drone activity.
- NATO's outgoing Deputy Secretary General, Mircea Geoan, indicated no intentional assault on NATO allies by Russia but labeled these actions as irresponsible and dangerous.
- Russian forces are tightening their grip around Pokrovsk in eastern Ukraine, aiming to dominate the Donbas area. The human toll of the conflict remains high, with a recent Russian missile strike in Lviv killing seven people and an artillery attack in Nikopol killing a 16-year-old girl.
- Sweden announced its 17th aid package for Ukraine, worth 340 million, including ammunition, combat boats, missiles, and camouflage gear.
- Russian glide bombs, weighing up to 1,500 kilograms, are causing significant damage in conflict areas in Ukraine.
- MI6 and CIA heads warn of an unprecedented threat to world order since the Cold War.
- Iranian officials denied reports of missile transfers to Russia, labeling them as psychological warfare.
- Japan's Ministry of Defense observed five Chinese navy vessels moving towards the Sea of Japan through the Tsushima Strait. Japan expressed concern over China's military assertiveness and incursions into Japanese airspace and territorial waters.
- Relations between Japan and Russia have worsened due to sanctions and territorial disputes over the Kuril Islands and Senkaku islands.
Monitored Intelligence for China - Sept. 13, 2024
News
Media
308
Government
Releases
42
City/State
Releases
36
Embassy
Releases
0
Foreign
Service
Advisories
0
Service
Advisories
0
Academic/
Think
Tank
7
Think
Tank
7
Podcasts
0
Videos
0
Social
Media
0
Business
Releases
1
Erudite Risk takes an all risks approach to intelligence reporting. We categorize key intelligence into one of 40 different risk intelligence categories.
The goal is to provide intelligence that allows decision makers to avoid being blindsided by what they may have missed, while informing them to make better decisions as well.
Risk Categories Reported on Today
Risk Category
Items Reported On
Geopolitical Conflict and Disputes
9
Crime
3
Terrorism
1
Shifting Geopolitical Alliances
9
Regulation
4
Political Scandal or Corruption
2
Climate Change
1
Epidemics and Pandemics
1
Natural Disasters
4
Accidents
1
South China Sea
1
IP Protection
1
Extreme Weather Events
2
Supply Chain Issues
2
Erudite Risk also includes operations categories so you can monitor the environment for better decision making. Everything is tied together--what happens in risk affects operations and what happens in the market impacts risk profiles.
We categorize key intelligence into one of 30 different operations intelligence categories.
Different roles and functions within the organization can monitor different key issue areas. HR may monitor employment, wages, regulations, labor and management relations, etc., while P&L leaders may monitor overall developing trends.
Operations Categories Reported on Today
Operations Category
Items Reported On
Investor Sentiment
1
Economic Growth
2
Bizdev-Partnering
3
Demographics
3
Asset Price Change
6
IP Protection
1
Trade Issues and Numbers
4
Protectionism
1
Energy Prices
1
Supply Chain Issues
1
Mergers & Acquisitions
1
China Focus: Demographic trends in China behind proposed retirement delay
Xinhua | English | News | Sept. 13, 2024 | Demographics
Chinese lawmakers are considering a draft decision to gradually raise the statutory retirement age in response to significant demographic changes. Key factors include increasing life expectancy, which has reached an average of 78.6 years and is projected to surpass 80 by 2030. The existing retirement ages, set in the 1950s, are seen as outdated given the current average years of education, which have risen to 11.05 years for the working-age population. China is also experiencing a shift towards a more aging society, with 297 million people aged 60 and above, projected to exceed 400 million by 2035. Additionally, despite a decline in the working-age population since 2012, approximately 860 million individuals still fall within this category. Adjusting retirement policies is viewed as necessary to leverage human resources and sustain economic growth.
China's Hainan accelerates work resumption in wake of super typhoon
Xinhua | English | News | Sept. 13, 2024 | Extreme Weather Events
Following Super Typhoon Yagi's landfall in Hainan on September 6, 2024, the province has initiated the resumption of work on nearly 70% of its construction projects. As of September 10, 1,979 out of 2,860 projects are back in operation. The government aims to support over 90% of businesses in key industrial parks, particularly those less affected by the typhoon, in resuming production by September 15. A goal has been set for a production resumption rate exceeding 95% across all key industrial parks by September 25. The typhoon caused significant damage across the island.
Super Typhoon Yagi Causes at Least USD11 Billion of Damage in China's Hainan Province
Yicai Global | English | News | Sept. 13, 2024 | Natural Disasters
Super Typhoon Yagi, one of the most powerful storms to strike China, has caused economic losses of at least CNY78.6 billion (USD11 billion) in Hainan province, impacting approximately 400,000 residents. The storm inflicted direct losses of CNY9.6 billion (USD1.4 billion) in Lingao county and caused combined losses exceeding CNY69 billion in Haikou, Wenchang, and Chengmai counties. Yagi made landfall near Wenchang on September 6, with wind speeds reaching 62 meters per second. It has resulted in four fatalities and 95 injuries, affecting critical infrastructure and sectors such as agriculture and services. Typhoon Rammasun, which struck in 2014, previously caused direct losses of CNY12 billion in the region.
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